Oral L-carnitine and pregnancy: real opportunity for narcoleptic women?

Comparison of pharmacokinetics of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine after single oral administration of L-carnitine in healthy volunteers.

PURPOSE To investigate the pharmacokinetics of L-carnitine (LC) and its analogues, acetyl-L-carnitine (ALC) and propionyl-L-carnitine (PLC) in healthy volunteers after single L-carnitine administration. METHODS Liquid L-carnitine (2.0 g) was administered orally as a single dose in 12 healthy subjects. Plasma and urine concentrations of L-carnitine, ALC and PLC were detected by HPLC. RESULTS...

Oral acetyl-L-carnitine therapy and insulin resistance.

Pregnancy increases urinary loss of carnitine and reduces plasma carnitine in Korean women.

This study compared plasma and urinary carnitine concentrations in pregnant and non-pregnant Korean women. The subjects were fifty pregnant women and thirty non-pregnant women aged 24-28 years. During the first trimester, dietary carnitine intakes in the pregnant women were much lower than in non-pregnant women (70.00 (SD 29.22) micromol/d), but over the course of pregnancy carnitine intake inc...

Carnitine Deficiency and Pregnancy

We present two cases of carnitine deficiency in pregnancy. In our first case, systematic screening revealed L-carnitine deficiency in the first born of an asymptomatic mother. In the course of her second pregnancy, maternal carnitine levels showed a deficiency as well. In a second case, a mother known with carnitine deficiency under supplementation was followed throughout her pregnancy. Both pr...

Oral health during pregnancy: A study from women with pregnancy

Madam, World health organization defines oral health as ‘‘being free of chronic mouth and facial pain, oral and throat cancer and other diseases and disorders that affect the mouth and oral cavity.”[1] Oral health is essential to the health and well‐being of both the pregnant mother and her baby.[2] The Pregnancy Risk Assessment Monitoring System reported that just 23‐43% of the pregnant women ...